September 16, 2025

USPS 2025: Pub 52 Revisions, IMmb Labels, and Vape-Device Packaging—A Shipping Playbook for Hemp/CBD Brands

USPS 2025: Pub 52 Revisions, IMmb Labels, and Vape-Device Packaging—A Shipping Playbook for Hemp/CBD Brands

Hemp and CBD brands shipping products through the US Postal Service (USPS) are facing significant regulatory changes in 2025, with critical updates that will reshape compliance, labeling, and packaging protocols. For those navigating cannabis compliance and licensing, these developments are central to risk management and operational continuity. Below, we break down everything hemp and CBD operators need to know about the new USPS requirements for 2025, focusing on Pub 52 revisions, the mandatory Intelligent Mail matrix barcode (IMmb), evolving packaging standards—especially for vape hardware—and renewed PACT Act enforcement priorities.

USPS Hemp Shipping 2025: What’s Changing?

Several USPS regulatory changes are impacting hemp and CBD shipments in 2025. These updates include major adjustments to mail labeling, outer packaging, and item classification—each carrying compliance risks for nonconforming brands. Staying current isn’t optional: stepped-up enforcement and electronic tracking make compliance essential for lawful shipment of permitted hemp-derived products.

Pub 52 (April 2025): Tougher Standards for Hazardous Material Packaging

In April 2025, USPS revised Publication 52 (Pub 52), the rulebook for hazardous, restricted, and perishable mail. These updates include:

  • Section 131 (Effective Jan 27, 2025): Imposes new minimum rigid outer packaging strength standards (edge crush or burst test ratings) for many hazardous materials. This affects shipping of products with lithium-ion batteries, such as certain vape devices.
  • Padded and Poly Bags Now Permitted for Certain Vape Shipments: Brands may use padded or poly mailers—if the battery is installed in a device and placed within a secondary, drop-test-capable inner container, and no hazardous material markings are otherwise required (see Federal Register, Jan 27, 2025).
  • Secondary Packaging Mandate: Anything with a lithium battery must first be in a tested container before entering a padded envelope; this will support compliance audits and incident investigations.

Key Takeaway: Double-check all vape device packaging—especially if your hardware includes lithium batteries. Upgrading packaging for USPS hemp shipping in 2025 is crucial for regulatory peace of mind.

IMmb Labels: The New Barcode Standard

Starting January 2025, USPS requires the GS1 DataMatrix Intelligent Mail matrix barcode (IMmb) on all domestic shipping labels. The IMmb:

  • Enables enhanced package visibility and auditability by USPS,
  • Integrates with shipping, track-and-trace, and compliance analytics software,
  • Is mandatory for all commercial mailers, including licensed hemp and CBD shippers.

If your label or fulfillment provider is not IMmb-ready, you risk rejected shipments and non-compliance penalties. Work closely now with your logistics partners to ensure IMmb adoption is complete across all shipping platforms.

Takeaway for Compliance Teams: Immediate label audits and technology upgrades should be prioritized. Confirm with label providers or internal systems that IMmb is active for each product class and account.


The PACT Act and USPS ENDS Rule: Persistent Barriers for Vapes

Despite the above packaging latitude, cannabis and hemp operators must remember that consumer shipping of most vape devices—including hemp-derived electronic nicotine delivery systems (ENDS)—remains flatly prohibited by USPS except for a handful of business-to-business (B2B), governmental, or academic shipments.

PACT Act Implications for Hemp/CBD Vape Shipments

  • The 2021 USPS ENDS Rule (based on the Prevent All Cigarette Trafficking (PACT) Act): Prohibits both nicotine and non-nicotine (hemp/CBD) vape cartridges and devices from being shipped DTC (direct to consumer) via USPS (read more).
  • B2B Exceptions: Only highly restricted, pre-approved B2B, government, or clinical research shipments are permitted.
  • Illicit Market Crackdown: In 2025, USPS signaled new enforcement sweeps targeting illicit vape mailings, using IMmb scans and intelligence to flag non-compliant packages (ATF guidance).

What This Means: Any business sending vape hardware or hemp-derived cartridges to consumers via USPS risks criminal and civil penalties. Internal audits should scrutinize carrier selection, product classification, and "adult signature" processes wherever B2B or government shipment claims are used.


Packaging Playbook: Getting Ready for USPS Hemp Shipping 2025

1. Shipping Label Compliance

  • IMmb Barcode: All labels must display a GS1 DataMatrix IMmb. Confirm with your partners and system integrators.
  • Tracking and Visibility: Internal compliance should monitor tracking data and audit return rates (rejections).

2. Outer Packaging Standards

  • Rigid Packaging: Enforce use of packaging that passes edge crush/burst test standards for hazardous materials (details in Pub 52 Section 131).
  • Poly/Padded Mailers: Only use if secondary, drop-test-rated container is used for battery-in-device shipments, and no HAZMAT marks are otherwise required.
  • Do Not Ship Mercury or Prohibited HAZMAT: Devices with metallic mercury remain banned outright by USPS.

3. Classification and Carrier Use

  • Vape Devices: Never ship DTC, even if hemp-derived. B2B options require pre-registration and special protocols. Review with legal/compliance teams.
  • Non-ENDS Hemp/CBD: USDA/FDA-compliant hemp (<0.3% THC), topicals, certain edibles, and other lawful products remain generally mailable—always review the latest guidance and state-by-state overlays.

4. Documentation and Auditing

  • Retention: Keep full records of all product classifications, shipping manifests, labeling, and packaging vendor test results for at least 2–3 years.
  • Enforcement Red Flags: USPS is cross-referencing IMmb shipments for suspicious frequency, destination patterns, and incomplete manifests as part of stepped-up enforcement.

Key Deadlines and Next Steps

  • January 27, 2025: Federal Register rule enacts new outer packaging standards for hazardous materials under Pub 52 Section 131.
  • January 2025: IMmb (Intelligent Mail matrix barcode) mandatory on all domestic USPS commercial shipping labels.
  • April 2025: Formal Pub 52 revisions take effect.

Action Items for Hemp and CBD Brands

For compliance officers and shipping leads:

  • Audit all mail processes: Update SOPs for Pub 52 revisions and the IMmb requirement.
  • Upgrade packaging: Ensure edge crush-tested or burst-tested outer containers; train warehouse/fulfillment staff on secondary containment for batteries.
  • Verify product classification: Never allow ENDS/vape devices into consumer-bound shipments.
  • IMmb preparations: Engage label providers and logistics teams for barcode technology upgrades now.
  • Monitor USPS/PACT guidance: Review USPS Publication 52 and the Federal Register for future amendments.

Conclusion: Staying Ahead of 2025 USPS Hemp Shipping Compliance

2025 is a landmark year requiring tighter compliance for all hemp and CBD shipping stakeholders. USPS hemp shipping 2025—with its updates to Pub 52, mandatory IMmb labels, revised vape/battery packaging standards, and ongoing PACT Act restrictions—demands robust, proactive internal controls. Cannabis and hemp brands that act now to upgrade documentation, tech infrastructure, and packaging protocols will be best positioned to avoid enforcement risks and seize emerging logistics opportunities.

Stay up to date and mitigate your regulatory risks by leveraging smart resources. For tailored guidance, compliance checklists, and real-time regulatory insights, visit CannabisRegulations.ai. Your shipping compliance is just a click away.