Is Delta-10 THC Legal in South Carolina?

May 22, 2026

Is delta-10 THC legal in South Carolina? Statute permits; AG Wilson's 2021 opinion treats all THC isomers as illegal. Federal H.R. 5371 ends synthetics Nov 12, 2026.

South Carolina

Cannabis & Hemp Overview

Last reviewed: May 22, 2026

Restricted. The South Carolina Hemp Farming Act, S.C. Code §46-55-10, does not separately list delta-10 THC, and the federal Farm Bill arguably covers hemp-derived isomers. Attorney General Alan Wilson's October 4, 2021 advisory opinion reads the statute as covering only delta-9 at the regulated threshold and treats other tetrahydrocannabinols as Schedule I substances under S.C. Code §44-53-190. Delta-10 falls inside that reading.

The opinion is advisory and has not been resolved by a published South Carolina appellate decision. SLED has used the opinion to support hemp retail enforcement. The federal H.R. 5371 §781 redefinition takes effect November 12, 2026 and excludes synthetic and chemically converted cannabinoids, which closes most of the delta-10 supply chain regardless of state law.

South Carolina Cannabis and Hemp Overview

South Carolina has not legalized medical or adult-use cannabis. Julian's Law (2014) created a narrow CBD pathway for intractable epilepsy patients. The Compassionate Care Act has passed the Senate multiple times but stalls in the House each session.

The state hemp program is administered by the South Carolina Department of Agriculture (SCDA). Delta-10 is an isomer of delta-9 produced almost exclusively through chemical conversion from hemp-derived CBD. That synthetic-conversion production method is what AG Wilson's 2021 opinion targets and what the federal H.R. 5371 redefinition excludes from the hemp definition. For the parallel framework, see our South Carolina delta-8 page.

What South Carolina Law Actually Says About Delta-10

S.C. Code §46-55-20 defines hemp using the federal Farm Bill formula. Delta-10 is not listed in the South Carolina Controlled Substances Act and is not separately addressed in the Hemp Farming Act.

The 2021 AG opinion expressly covers "THC and THC isomers including delta-8 THC." The reasoning extends naturally to delta-10. The opinion's analysis turns on the definition of "tetrahydrocannabinols" in §44-53-190 and treats synthetic isomers as outside the hemp statute and inside Schedule I.

How Enforcement Has Played Out

SLED has used the 2021 AG opinion to support seizures, arrests, and prosecutions targeting synthetic-conversion cannabinoid retailers. The most prominent action is Operation Ganjapreneur, announced December 9, 2025, which produced 12 state grand jury indictments and the seizure of roughly 15 tons of hemp-derived THC products. Industry counsel has filed legal challenges arguing the products were Farm Bill compliant.

Three competing bills are in the 2025-2026 session. H 3924 creates a hemp-derived consumables licensing framework and expressly prohibits synthetic cannabinoid products, which would cover delta-10. H 4759 covers intoxicating hemp beverages. H 3935 is a parallel consumables framework. None has passed both chambers as of May 22, 2026.

What This Means for Retailers Selling Delta-10 in South Carolina

What This Means for Consumers Buying Delta-10 in South Carolina

Delta-10 is available at some South Carolina hemp retailers despite the AG opinion, but enforcement risk is elevated. Consumers should verify products carry a current COA from an accredited lab and that finished-product testing confirms the cannabinoid profile on the label. Delta-10 produces effects similar to delta-9 THC, and metabolites overlap with delta-9 on most standard drug tests. The November 12, 2026 federal change will narrow what is available at hemp retail nationwide.

Pending Federal Change

H.R. 5371 §781, signed November 12, 2025, explicitly excludes synthetic and chemically converted cannabinoids from the federal hemp definition. Delta-10 is produced almost exclusively through chemical conversion of hemp-derived CBD or delta-9, which places it inside the excluded category. The provision takes effect November 12, 2026. After that date, delta-10 products lose federal Farm Bill protection regardless of how the South Carolina statute is read. For background see our potential revisions to the 2018 Farm Bill explainer.

Frequently Asked Questions

Is delta-10 THC legal in South Carolina in 2026?
Statute arguably permits it; AG Wilson's October 4, 2021 advisory opinion reads it as illegal; SLED enforces the AG position. Treat the product as high-risk in South Carolina.

What is delta-10 and how is it different from delta-9?
Delta-10 is an isomer of delta-9 THC. It is produced through chemical conversion from hemp-derived CBD or delta-9. It is structurally similar to delta-9 but with the double bond at a different position, which affects pharmacology and stability.

Does the 2021 AG opinion mention delta-10 by name?
The opinion is titled to cover "THC and THC isomers including delta-8 THC." Its reasoning treats all non-delta-9 tetrahydrocannabinols as Schedule I and naturally extends to delta-10.

Does delta-10 show up on a drug test?
Yes. Delta-10 metabolites overlap with delta-9 THC metabolites on most standard tests.

Can I order delta-10 online to South Carolina?
Online sellers ship today, but SLED has seized synthetic-isomer inventory from in-state retailers. Federal November 12, 2026 change applies.

How does delta-10 compare to delta-8 in South Carolina?
See our South Carolina delta-8 page. The AG opinion and enforcement posture apply to both.

What changes November 12, 2026?
The federal hemp redefinition excludes synthetic and chemically converted cannabinoids. Delta-10 loses federal Farm Bill protection on that date.


This page is provided for informational purposes by ComplyAssistAI LLC and is not legal advice. Hemp and cannabis law in South Carolina changes frequently. For business compliance questions, consult a South Carolina-licensed cannabis attorney. Find one in our Cannabis Lawyer Directory.

South Carolina

Cannabis & Hemp Key Facts

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Legal Status:
Delta-10 THC

Restricted

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Applicable Law

South Carolina Hemp Farming Act, S.C. Code §46-55-10; AG Opinion (Oct. 4, 2021); SLED enforcement

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Product Potency Limits

No statutory restriction. AG opinion treats synthetic THC isomers as Schedule I. Active enforcement risk.

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License Required?

No

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